Since 2020, aggregated from related topics
Matrix metalloproteinases (MMPs) are a family of enzymes that play a crucial role in the remodeling of the extracellular matrix, which is the framework of connective tissue in the body. These enzymes are involved in a wide range of physiological processes, such as tissue repair, development, and cell migration. However, dysregulation of MMP activity has been implicated in various pathological conditions, including cancer, arthritis, and cardiovascular diseases. Research in this area focuses on understanding the mechanisms of MMP regulation, their role in disease progression, and the development of MMP inhibitors as potential therapeutic agents.